Northwestern Proteomics plays a pivotal role in advancing 21st century biology through strategic partnerships with multidisciplinary investigators from across Northwestern and beyond. Our joint research initiatives aim to accelerate the development of next-generation technologies for comprehensive proteoform analysis. The resulting innovations will revolutionize drug and diagnostics discovery and development, ushering in a new era of precision medicine.

The National Resource for Translational and Developmental Proteomics (NRTDP) is dedicated to accelerating a significant shift in how protein molecules are analyzed by mass spectrometry, with a focus on intact protein measurements.

The Consortium for Top-Down Proteomics is a non-profit corporation with members from academic institutions, corporations, and government agencies. Their Mission is to promote collaboration, education, and innovative research that will accelerate the Human Proteoform Project and Atlas initiatives.


The Human Proteoform Project and Atlas is an ambitious initiative to generate a definitive reference set of all human proteoforms.  

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P. Hande Ozdinler, Ph.D., Assistant Professor, and Neil Kelleher, Ph.D., Professor at Northwestern University Feinberg School of Medicine in Chicago received $240,000 to compare protein dynamics within healthy and vulnerable upper motor neurons as an early detection marker and novel disease mechanism. 


P. Hande Ozdinler, Northwestern University

Neil Kelleher, Northwestern University

Paul Thomas, Northwestern University

With the support of The Paul G. Allen Family Foundation, Neil Kelleher will explore how human blood cells – B-cells – mature from their beginnings in our bone marrow to those that protect us from infection.


Neil Kelleher, Northwestern University

Ioanna Ntai, Northwestern University

Rebekah Gundry, Medical College of Wisconsin

Richard LeDuc, Northwestern University

Northwestern Proteomics is a member of UIC’s NNCCS Center. If you have a project which relates to the study of addiction mechanisms in the central nervous system, please contact the center at the link below.


Jonathan Sweedler, University of Illinois

Neil Kelleher, Northwestern University

Sandra Rodriguez-Zas, University of Illinois


P01 Integrating Mechanistic Insights from Diverse Models to Prevent CMV Reactivation Following Transplantation,

Investigators from Northwestern University:

Michael Abecassis, Mary Hummel, Xunrong Luo, Zheng (Jenny) Zhang, Kristy Wolniak, and Neil Kelleher


Neil Kelleher is a member of Northwestern Medicine’s Robert H. Lurie Comprehensive Cancer Center and Brain Tumor Institute. His team develops new technologies for complex mixture analysis using Fourier-Transform Mass Spectrometry for targeted applications in proteomics and metabolomics.


A team from Northwestern University, in collaboration with Thermo Fisher Scientific, plans to overcome this major barrier in disease research by developing a new kind of mass spectrometer that combines the advantages of Time-of-Flight (TOF) and Fourier Transform (FT) analyzers.

Investigators from Northwestern University:

Neil Kelleher, Philip Compton, and Navdeep Chandel

Meet some of our faculty collaborators.

Brain Tumors

Vice Chair for Clinical Affairs, Department of Neurological SurgeryLavin/Fates Professor of Neurological Surgery


Professor in Cell and Molecular Biology

Cell-free Systems

Professor of Chemical and Biological Engineering

Organ Rejection

Professor in Medicine-Gastroenterology and Hepatology and Surgery-Organ Transplantation

Methane Oxidation

Weinberg Family Distinguished Professor of Life Sciences

Cardiovascular Disease

Associate Professor in Medicine-Cardiology/Preventive Medicine