In this service line, proteins are identified after an in-gel or in-solution digestion.
Proteins are separated (or not) prior to digestion. Cost for this analysis depends on the complexity of sample preparation and number of samples that are being analyzed.
Gundry RL, White MY, Murray CI, Kane LA, Fu Q, Stanley BA, Van Eyk JE “Preparation of proteins and peptides for mass spectrometry analysis in a bottom-up proteomics workflow.” Curr Protoc Mol Biol, 2009, Chapter 10() p. Unit10.25.
Summary | Full Text (PMC) | Full Text (DOI)
“The challenge of the proteome dynamic range and its implications for in-depth proteomics.” Proteomics, 2013, 13(5) p. 723-6.
Q Exactive HF