Northwestern Proteomics, a Chemistry of Life Processes Institute-affiliated center, together with an interdisciplinary team of Northwestern mathematicians, experimentalists, biomedical engineers, and biochemists, recently published two academic papers announcing a new, game-changing technique for characterizing and identifying proteins with extreme precision.
For the first time, using the commercially available Orbitrap mass analyzer system, researchers successfully integrated two mass spectrometry (MS) approaches: native or top-down MS and, an even more pioneering technique, individual ion mass spectrometry (I2MS), both pioneered by the Kelleher Research Group. The powerful and new approach, two-and-a half years in the making, will help illuminate complex questions within fundamental biology and transform understanding of disease and infection and to accelerate the design of new therapies.
Original story by Lisa La Vallee posted on March 2, 2020 by Chemistry of Life Processes Institute.