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Northwestern Medicine investigators have discovered novel mechanisms underlying a specific transcription factor essential for elongation control, the process of synthesizing RNA from DNA, according to findings published in Molecular Cell. “This is another superb molecular study by Dr. Yuki Aoi whom […]
Chemistry of Life Processes Institute (CLP) director Neil L. Kelleher and members of the CLP and Northwestern Proteomics team welcomed U.S. Congresswoman Jan Schakowsky from the 9th District of Illinois to Silverman Hall today to discuss the promise and potential of the Human Proteoform […]
Eight years ago, an international team of researchers proposed that the term “proteoform” be adopted to describe the vast number of forms of protein products from our genes—including changes due to genetic variations, alternative RNA splicing, and post-translational […]
This episode of Northwestern University Feinberg School of Medicine’s Breakthroughs Podcast features Neil Kelleher, PhD, director of Northwestern Proteomics and Chemistry of Life Processes Institute. Millions of molecular proteins are swimming through our body’s cells and many studies […]

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Northwestern Medicine scientists have developed a new method to analyze the protein composition of intact nucleosomes without losing combinatorial information present in chromatin. The technique, called Nuc-MS, could help scientists more efficiently uncover the mechanisms behind mutation-driven diseases […]